Table 1.
Echocardiography data of JDP2-overexpressing and WT mice.
| Time of Dox-absence | 1 week | 5 week | ||
|---|---|---|---|---|
| n | WT | JDP2 | WT | JDP2 |
| 15 | 11 | 8 | 11 | |
| Left ventricular end diastolic diameter (LVEDD), longitudinal (mm) | 3.83 ± 0.60 | 3.88 ± 0.50 | 3.38 ± 0.44 | 3.93 ± 0.51* |
| Left ventricular end systolic diameter (LVESD), cross sectional (mm) | 2.39 ± 0.61 | 2.85 ± 0.46 | 1.83 ± 0.51 | 2.63 ± 0.55* |
| FS, cross sectional (%) | 38.1 ± 7.6 | 27.4 ± 4.8* | 46 ± 9 | 29 ± 7* |
| EF, cross sectional (%) | 64.6 ± 10.4 | 58.8 ± 9.3* | 66.0 ± 5.4 | 34.5 ± 7.0* |
| SV (µl) | 49.1 ± 13.0 | 37.3 ± 6.4 | 45.7 ± 8.2 | 28.4 ± 4.1* |
| CO (ml/min) | 23.0 ± 4.8 | 19.4 ± 3.3* | 22.1 ± 5.1 | 13.6 ± 2.6* |
*p ≤ 0.05 comparing age-matched WT and JDP2 mice (t-Test).