Figure 6.
Effect of new Ru(ƞ6-p-cymene) on oxidative stress resistance and intracellular ROS levels in wild-type C. elegans. (A) Pretreatment of complexes 1–4 significantly (P < 0.001) promote the resistance to juglone-induced oxidative stress. (B) Quantification of intracellular ROS levels in N2 C. elegans using H2DCF-DA. The relative formation of juglone-induced intracellular ROS was reduced significantly (P < 0.05/P < 0.001) after treated with complexes 1–4. Data are presented as mean ± SEM of three independent runs (n = 25–30/replicate), P values were calculated by Bonferroni post hoc test. *P < 0.05 and **P < 0.001.