Table 2.
HLA-DRB1 and HLA-DQB1 allele frequencies in ASD patients and healthy controls.
| HLA alleles | ASD N subjects = 474 |
HC N subjects = 350 |
pcvalue |
|---|---|---|---|
| % (n alleles) | % (n alleles) | ||
| DRB1 | |||
| DRB1*04 | 12.13 (115) | 15.57 (109) | NS |
| DRB1*07 | 12.87 (122) | 14.14 (99) | — |
| DRB1*13 | 13.19 (125) | 13.57 (95) | — |
| DRB1*11 | 16.03 (152) | 9.14 (64) | — |
| DRB1*15 | 13.61 (129) | 10.29 (72) | — |
| DRB1*17 | 9.28 (88) | 13.14 (92) | — |
| DRB1*01 | 8.97 (85) | 10.57 (74) | — |
| DRB1*14 | 4.01 (38) | 4 (28) | — |
| DRB1*16 | 3.48 (33) | 2.57 (18) | — |
| DRB1*08 | 2.43 (23) | 3.57 (25) | — |
| DRB1*12 | 1.69 (16) | 1 (7) | — |
| DRB1*09 | 1.37 (13) | 1 (7) | — |
| DRB1*10 | 0.42 (4) | 1 (7) | — |
| DRB1*03 | 0.21 (2) | 0.29 (2) | — |
| DRB1*18 | 0.32 (3) | 0.14 (1) | — |
| DQB1 | |||
| DQB1*06 | 24.68 (234) | 22 (154) | — |
| DQB1*02 | 20.57 (195) | 25.57 (179) | — |
| DQB1*07 | 22.05 (209) | 16.29 (114) | — |
| DQB1*05 | 18.46 (176) | 18 (126) | — |
| DQB1*08 | 7.81 (74) | 11 (80) | — |
| DQB1*04 | 2.74 (26) | 3.86 (28) | — |
| DQB1*09 | 3.59 (34) | 2.71 (19) | — |
NS: statistically non significant.