Table 2.
Linear regression analysis for the association between Lp(a) level with coronary severity measured by Gensini score in patients with stable coronary artery disease.
| Variables | Standardized coefficients | p |
|---|---|---|
| Univariate analysis | ||
| Lp(a) (log-transformed) | 0.104 | <0.001 |
| Multivariate analysis adjusting for age, gender and LDL-C | ||
| Lp(a) (log-transformed) | 0.092 | <0.001 |
| Age | 0.103 | <0.001 |
| Gender (male vs. female) | 0.137 | <0.001 |
| LDL-C | 0.095 | <0.001 |
| Multivariate analysis adjusting for traditional cardiovascular risk factors | ||
| Lp(a) (log-transformed) | 0.098 | <0.001 |
| Age | 0.124 | <0.001 |
| Gender (male vs. female) | 0.112 | <0.001 |
| BMI | 0.015 | 0.540 |
| History of hypertension (with vs. without) | 0.018 | 0.466 |
| History of diabetes mellitus (with vs. without) | 0.062 | 0.014 |
| History of current smoking (with vs. without) | 0.066 | 0.017 |
| Family history of premature CAD | 0.010 | 0.684 |
| TC | −0.017 | 0.790 |
| LDL-C | 0.108 | 0.046 |
| HDL-C | −0.021 | 0.527 |
| TG (log-transformed) | 0.032 | 0.347 |
P values were from linear regression. Two-tailed p < 0.05 was considered statistically significant. CAD: coronary artery disease, BMI: body mass index, Lp(a): lipoprotein(a), TC: total cholesterol, LDL-C: LDL cholesterol, HDL-C: HDL cholesterol, non-HDL-C: non-HDL cholesterol, TG: triglyceride.