Table 5.
Cox proportional hazard regression analysis for the independent predictors of major adverse cardiovascular events.
| Variables | HR | 95% CI | p |
|---|---|---|---|
| Age | 1.005 | 0.990–1.021 | 0.499 |
| Gender (male vs. female) | 1.420 | 0.957–2.105 | 0.081 |
| BMI | 0.980 | 0.930–1.033 | 0.446 |
| History of hypertension (with vs. without) | 1.173 | 0.845–1.628 | 0.339 |
| History of diabetes mellitus (with vs. without) | 1.861 | 1.335–2.594 | <0.001 |
| History of current smoking (with vs. without) | 1.158 | 0.813–1.650 | 0.416 |
| Family history of premature CAD | 0.694 | 0.284–1.695 | 0.422 |
| Gensini score | 1.031 | 1.024–1.038 | <0.001 |
| Coronary revascularization | 1.096 | 0.803–1.495 | 0.563 |
| LVEF, % | 0.977 | 0.955–0.998 | 0.036 |
| TC | 0.997 | 0.683–1.456 | 0.997 |
| LDL-C | 0.979 | 0.643–1.490 | 0.921 |
| HDL-C | 0.981 | 0.524–1.837 | 0.952 |
| TG | 1.006 | 0.859–1.178 | 0.944 |
| Lp(a)* (log-transformed) | 1.291 | 1.091–1.527 | 0.003 |
P values were from Cox proportional hazard regression. Two-tailed p < 0.05 was considered statistically significant. CAD: Coronary artery disease, BMI: body mass index, LVEF: left ventricular ejection fraction; Lp(a): lipoprotein(a), TC: total cholesterol, LDL-C: LDL cholesterol, HDL-C: HDL cholesterol, non-HDL-C: non-HDL cholesterol, TG: triglyceride. *Per standard deviation increase in the log transformed Lp(a) levels.