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Comparison of degenerate TALEN sites as potential off-target sites in the bovine genome to variants called from whole genome shotgun sequencing reads.
| Degeneracy in a TALEN pair | Genome-wide off-target sites | Variants from whole genome shotgun sequencing reads* | |
|---|---|---|---|
| 1601 | 1602 | ||
| 0_0 | 1 | 1 | 1 |
| 1_4 | 0 | 0 | 0 |
| 1_5 | 0 | 0 | 0 |
| 4_2 | 1 | 0 | 0 |
| 3_3 | 0 | 0 | 0 |
| 2_5 | 3 | 0 | 0 |
| 3_4 | 2 | 0 | 0 |
| 3_5 | 14 | 0 | 0 |
| 4_4 | 6 | 0 | 0 |
| 5_4 | 60 | 0 | 0 |
| 5_5 | 229 | 0 | 0 |
| Total | 316 | 1 | 1 |
*Within 20 bp of a degenerate TALEN sites.
