Table 3.
Association between factor XIII (FXIII) levels before thrombolysis and the severity and etiology of the stroke.
| Severity of Stroke | |||||
|---|---|---|---|---|---|
| NIHSS 0–5 (n = 37) | NIHSS 6–10 (n = 48) | NIHSS 11–15 (n = 21) | NIHSS > 15 (n = 23) | P-value* | |
| FXIII activity (%) | 129.7 ± 39.9 | 126.2 ± 39.6 | 125.6 ± 26.4 | 120.5 ± 32.3 | 0.808 |
| FXIII-A2B2 (mg/l) | 23.1 ± 7.8 | 22.6 ± 9.5 | 21.8 ± 5.0 | 21.1 ± 5.4 | 0.805 |
| Etiology of Stroke | |||||
| Small vessel infarcts (n = 14) | Large vessel thrombosis (n = 49) | Cardio-embolic (n = 27) | P-value† small vessel infarcts vs. cardioembolic | P -value † atherothrombotic vs. cardioembolic | |
| FXIII activity (%) | 145.6 ± 33.4 | 130.5 ± 38.3 | 117.5 ± 24.0 | 0.038 | 0.012 |
| FXIII-A2B2 (mg/l) | 25.5 ± 7.4 | 22.8 ± 8.3 | 20.8 ± 4.8 | 0.160 | 0.058 |
Results are expressed as mean ± standard deviation. NIHSS, National Institute of Health Stroke Scale; n, number of patients. *Univariate analysis (ANOVA); †ANOVA with Bonferroni post hoc test; atherothrombotic: small vessel infarcts + large vessel thrombosis.