Fig. 1.
Effect of H. polygyrus infection on EAE in C57BL/6 females. Immunization scheme (a). At Day 0, the mice of the EAE group were immunized with MOG35–55 emulsified in CFA containing M. tuberculosis H37RA strain; they received B. pertussis toxin (Ptx) immediately afterwards and again 48 h later. On Day 21 after immunization, the mice were infected with L3 H. polygyrus (b, arrowhead). The mice were examined 3 or 6 days post-infection. Clinical characteristics of EAE after nematode treatment (b). The results of one representative experiment are presented as the mean ± SD of six mice per group. # p < 0.05 compared with EAE group assessed by ANOVA