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Frequencies of driver gene aberrations in lung adenocarcinoma (LADC). The frequencies are shown for mutations in EGFR, KRAS, BRAF, and HER2, fusions involving ALK, RET, ROS1, NRG1, and BRAF and skipping of MET exon 14. The data were obtained from a Japanese cohort (319 cases from National Cancer Center Hospital) and a US cohort (230 cases from the TCGA study). This figure was modified from our previous reports13,19).
