(a) Response of Quin-C18 to glucose or fructose within different SiHGs and in a HG in pH 7.2 phosphate buffer. Incrementing glucose concentrations (from 0 to 100 with 20 mM interval) and 0, 1, 2, 4, 7, and 10 mM of fructose were used before purging the lenses with final buffer. Bioaffinity, Aspire 1day, and OptixAqua are SiGHs and Dailies is a HG contact lens. (b) Similar response to the glucose or fructose from Quin-C18-doped lenses stored in water for 3 months.