TABLE 5 .
Relation of ex vivo cytokine concentrations to follow-up of subjects
| Result or parameter at follow-up |
Ex vivo cytokine concn (pg/ml) (range) or the P valuea |
|||||
|---|---|---|---|---|---|---|
| GM-CSF | IL-1β | IFN-γ | IL-2 | IL-13 | TNF-α | |
| Outcome | ||||||
| Improved (n = 18) | 244 (0–1,744) | 465 (0–3,998) | 303 (0–1,854) | 562 (1–2,013) | 42 (0–854) | 6,689 (1–29,374) |
| Not improved (n = 8) | 182 (3–1,478) | 385 (3–3,067) | 859 (12–1,847) | 771 (11–2,058) | 48 (3–122) | 465 (3–6,692) |
| P value | 0.868 | 1.00 | 0.317 | 0.657 | 0.781 | 0.085 |
| IDCF titer | ||||||
| Positive (n = 12) | 360 (5–1,478) | 364 (16–3,998) | 560 (23–1,847) | 679 (28–2,058) | 60 (5–301) | 6,662 (57–29,374) |
| Negative (n = 14) | 170 (0–1,744) | 470 (0–2,084) | 211 (0–1,854) | 571 (1–2,013) | 26 (0–854) | 809 (1–14,206) |
| P value | 0.304 | 0.441 | 0.136 | 0.472 | 0.382 | 0.165 |
| Chest imaging | ||||||
| Improved (n = 15) | 324 (5–1,744) | 455 (0–3,453) | 311 (12–1,854) | 1,072 (14–2,058) | 52 (2–854) | 3,785 (57–24,253) |
| Not improved (n = 10) | 126 (0–1,478) | 369 (1–3,998) | 448 (0–1,180) | 499 (1–2,013) | 36 (0–104) | 905 (1–29,374) |
| P value | 0.120 | 0.912 | 0.471 | 0.183 | 0.222 | 0.346 |
| Antifungal therapy | ||||||
| Yes (n = 12) | 232 (0–1,478) | 456 (1–3,998) | 211 (0–1,687) | 166 (1–1,913) | 36 (0–158) | 2,206 (1–29,374) |
| No (n = 14) | 225 (3–1,744) | 435 (0–1,697) | 595 (12–1,854) | 1,053 (11–2,058) | 67 (2–854) | 5,200 (3–8,908) |
| P value | 0.797 | 0.440 | 0.181 | 0.031 | 0.304 | 0.877 |
a
The P values are shown in italic type in the table. The italic boldface P value indicates statistical significance.