Table 4.
The rotavirus vaccination Cauliflower Value Toolbox used in a mature healthcare market, outcome per cauliflower floret added in the analysis.
| Cauliflower floret number | Type of analysis | Item | New | Existing | Incremental | ICUA | Cost Vaccine |
|---|---|---|---|---|---|---|---|
| 1a/1b/1c | Simple ICUA | Cost | €862,034 | €727,500 | €134,534 | €25,001 | €75.03 |
| QALY | −3.12 | −8.50 | 5.38 | ||||
| 1a/1b/1c/2a | + indirect effect | Cost | €799,469 | €727,500 | €71,969 | €11,508 | €84.85 |
| QALY | −2.25 | −8.50 | 6.25 | ||||
| 1a/1b/1c/2a/3a | + indirect effect + QoC | Cost | €751,445 | €747,500 | €3,945 | €831 | €88.37 |
| QALY | −1.90 | −6.65 | 4.75 | ||||
| 1a/1b/1c/2a/3a/2b | + indirect effect + QoC + caregiver | Cost | €751,445 | €747,500 | €3,945 | €638 | €92.55 |
| QALY | −2.43 | −8.62 | 6.18 | ||||
| 1a/1b/1c/2a/3a/2b/2c | + indirect effect + QoC + caregiver+ non-healthcare cost | Cost | €981,485 | €1,395,500 | −€414,015 | Savings | €141.15 |
| QALY | −2.43 | −8.62 | 6.18 | ||||
| 1a/1c/2b | + caregiver | Cost | €862,034 | €727,500 | €134,534 | €80,961 | €64.22 |
| QALY | −0.89 | −2.55 | 1.66 | ||||
| 1a/1c/2a/2b | + caregiver + indirect effect | Cost | €799,469 | €727,500 | €71,969 | €37,693 | €72.22 |
| QALY | −0.64 | −2.55 | 1.91 | ||||
| 1a/1b/1c/3a | + QoC | Cost | €794,230 | €747,500 | €46,730 | €11,587 | €81.32 |
| QALY | −2.62 | −6.65 | 4.03 | ||||
| 1a/1b/1c/2c | + non-healthcare cost | Cost | €1,175,666 | €1,375,500 | −€199,834 | Savings | €113.91 |
| QALY | −3.12 | −8.50 | 5.38 |
ICUA, incremental cost-utility analysis; QALY, quality-adjusted life-year; QoC, quality of care