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. 2018 May 16;9:41. doi: 10.1186/s40104-018-0257-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Topology analysis of metabolic pathways identified among the feeding, 24 h fasting and 48 h fasting comparisons. The X-axis represents the pathway impact, and Y-axis represents the pathway enrichment. Larger sizes and darker colors represent greater pathway enrichment and higher pathway impact values, respectively. I: Linoleic acid metabolism; II: Arginine and proline metabolism; III: Sphingolipid metabolism; IV: Alanine, aspartate and glutamate metabolism; V: Pantothenate and CoA biosynthesis