Fig. 4.

Histopathology of choroidal lesion. Gross globe (A) with higher power (B) showing multifocal choroidal infiltrates (arrows). Hematoxylin and eosin stain showing artifactual separation of the retina from the retinal pigment epithelium and choroid and a full thickness nodular choroidal lesion devoid of normal choroidal vasculature (C). Grocott's methenamine silver stain of an adjacent section (D) reveals small round organisms within the histiocytes that stain positively for Periodic acid -Schiff (E). Higher power (F) reveals budding organisms with prominent capsules (G) consistent with Cryptococcus neoformans.