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GLI-1 and SMO expression in the transformed cells. GLI-1 and SMO expression in the CSE-induced transformed cells at the (a) 15th, (b) 25th, (c) 35th, and (d) 45th generation was detected by Western blot. Nontreated (normal) and CSE + cycl-treated cells were used as controls. CSE: Cigarette smoke extract; Cycl: Cyclopamine; GLI: Glioma-associated oncogene homolog; SMO: Smoothened.
