Table S1.

Logistic regression analysis of different SBP trajectory groups to parameters of kidney damage

Parameters of kidney damage||	Groups	OR (95% CI)
		Model 1*	Model 2†	Model 3‡	Model 4§
eGFR <60 ml·min−1·1.73 m−2	Low-stable group	1	1	1	1
	Moderate-stable group	1.96 (1.24–3.07)	1.58 (1.01–2.50)	1.59 (0.98–2.60)	1.45 (0.86–2.46)
	Moderate increasing group	2.46 (1.46–4.12)	1.63 (0.96–2.77)	1.65 (0.90–3.03)	1.37 (0.84–2.78)
	Elevated decreasing group	3.20 (1.96–5.22)	2.22 (1.34–3.65)	2.15 (1.22–3.80)	1.74 (0.86–3.50)
	Elevated stable group	4.57 (2.76–7.56)	2.81 (1.68–4.72)	2.70 (1.51–4.83)	2.01 (0.90–4.50)
	P-trend	<0.001	0.001	0.009	0.446
	Slope of SBP			0.92 (0.79–1.06)	0.96 (0.81–1.15)
	SBP_06				1.00 (0.99–1.01)
Positive urinary protein	Low-stable group	1	1	1	1
	Moderate-stable group	1.57 (1.10–2.24)	1.50 (1.04–2.15)	1.46 (1.00–2.13)	1.34 (0.89–2.03)
	Moderate increasing group	3.21 (2.17–4.73)	2.97 (2.00–4.43)	1.99 (1.26–3.14)	1.68 (0.98–2.89)
	Elevated decreasing group	2.87 (1.95–4.23)	2.67 (1.80–3.97)	3.20 (2.02–5.06)	2.63 (1.49–4.64)
	Elevated stable group	4.17 (2.79–6.42)	3.82 (2.52–5.79)	3.17 (1.99–5.05)	2.39 (1.25–4.56)
	P-trend	<0.001	<0.001	<0.001	0.007
	Slope of SBP			1.22 (1.08–1.37)	1.29 (1.12–1.50)
	SBP_06				1.00 (0.99–1.01)
eGFR <60 ml·min−1· 1.73 m−2 and/or positive urinary protein	Low-stable group	1	1	1	1
	Moderate-stable group	1.65 (1.24–2.21)	1.47 (1.10–1.97)	1.40 (1.02–1.90)	1.25 (0.89–1.75)
	Moderate increasing group	2.84 (2.05–3.94)	2.27 (1.62–3.17)	1.64 (1.12–2.41)	1.31 (0.83–2.07)
	Elevated decreasing group	2.93 (2.13–4.03)	2.40 (1.74–3.33)	2.59 (1.78–3.77)	1.98 (1.24–3.17)
	Elevated stable group	4.16 (2.97–5.83)	3.18 (2.25–4.50)	2.63 (1.78–3.87)	1.86 (1.08–3.19)
	P-trend	<0.001	<0.001	<0.001	0.034
	Slope of SBP			1.11 (1.01–1.23)	1.19 (1.06–1.35)
	SBP_06				1.01 (1.00–1.01)
eGFR reduced ≥30%	Low-stable group	1	1	1	1
	Moderate-stable group	1.12 (0.80–1.57)	1.06 (0.75–1.48)	1.09 (0.74–1.62)	1.13 (0.73–1.75)
	Moderate increasing group	1.21 (0.79–1.84)	1.07 (0.69–1.65)	1.36 (0.79–2.35)	1.40 (0.73–2.69)
	Elevated decreasing group	1.86 (1.28–2.70)	1.67 (1.14–2.46)	1.77 (1.09–2.88)	1.92 (1.01–3.64)
	Elevated stable group	1.89 (1.24–2.87)	1.64 (1.06–2.53)	2.10 (1.23–3.58)	2.20 (1.03–4.71)
	P-trend	0.001	0.006	0.011	0.119
	Slope of SBP			0.87 (0.76–1.01)	0.86 (0.73–1.02)
	SBP_06				0.99 (0.98–1.01)

*Model 1: With different parameters as the dependent variable, different BP trajectory group as independent variable, low-stable group as the control group; ^†Model 2: Adjusting for age, gender on the basis of Model 1; ^‡Model 3: Adjusting for FBG, BMI, eGFR, high cholesterol, smoking, alcohol consumption, physical activity, taking antihypertensive medications, slope of SBP on the basis of Model 2; ^§Model 4: Adjusting for SBP in 2006 on the basis of Model 3; ^||Parameters of kidney damage: “eGFR ≥60 ml·min⁻¹·1.73 m⁻²” = 0, “eGFR <60 ml·min⁻¹ ·1.73 m⁻²” = 1; “negative urine protein” = 0, “positive urinary protein” = 1; “eGFR ≥60 ml·min⁻¹ ·1.73 m⁻² and negative urine protein” = 0, “eGFR <60 ml·min⁻¹ ·1.73 m⁻² or urine protein positive” = 1; “eGFR decline <30%” = 0, “eGFR decline ≥30%” = 1; gender: “female” = 0, “male” = 1; high cholesterol, smoking, alcohol consumption, exercise, taking antihypertensive medications: “No” = 0,”Yes” = 1. SBP: Systolic blood pressure; BMI: Body mass index; FBG: Fasting blood glucose; eGFR: Estimated glomerular filtration rate; BP: Blood pressure; OR: Odds ratio; CI: Confidence interval.