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. 2018 May 20;131(10):1214–1219. doi: 10.4103/0366-6999.231515

Figure 1.

Figure 1

Plasmalogen-derived Cl2 oxidation products. The vinyl ether bond of plasmalogens is targeted by Cl2 resulting in 2-chlorofatty aldehyde production including 2-Cl-Pald and 2-Cl-Sald. The 2-chlorofatty aldehydes are either oxidized to the 2-chlorofatty acids, 2-Cl-PA and 2-Cl-SA, or reduced to the 2-chlorofatty alcohols, 2-chloropalmitoyl alcohol and 2-chlorostearoyl alcohol. Alternatively, nucleophilic attack of 2-chlorofatty aldehydes by GSH results in either palmitaldehyde or stearaldehyde GSH adduct formation. GSH: Glutathione. Source: Ford DA, Honavar J, Albert CJ, Duerr MA, Oh JY, Doran S, et al. Formation of chlorinated lipids post-chlorine gas exposure. J Lipid Res 2016;57:1529-40.