Table 1.

Details of studies and datasets used for analyses

Exposure/outcome	Consortium	Participants	Web source if publicly available
Serum magnesium	CHARGE and replication studies [22]	23,829 individuals of European ancestry	Not available
Coronary artery disease	CARDIoGRAMplusC4D consortium’s 1000 Genomes-based GWAS [23]	184,305 individuals (60,801 CAD cases and 123,504 non-cases) of mainly European (77%) and Asian (19%) ancestry	www.cardiogramplusc4d.org/
Blood pressure	ICBP [29]	69,395 individuals of European ancestry	www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000585.v1.p1
Lipids	GLGC [30]	188,577 individuals of European ancestry	csg.sph.umich.edu/abecasis/public/lipids2013/
Glycaemic traits	MAGIC [31]	46,186 non-diabetic individuals of European ancestry	www.magicinvestigators.org/
Body mass index	GIANT [32]	339,224 individuals of mainly European (95%) ancestry	portals.broadinstitute.org/collaboration/giant/index.php/GIANT_consortium
Waist-to-hip ratio	GIANT [33]	224,459 individuals of mainly European (94%) ancestry	portals.broadinstitute.org/collaboration/giant/index.php/GIANT_consortium
Smoking	TAGC [34]	74,053 individuals of European ancestry	www.med.unc.edu/pgc/results-and-downloads

CHARGE Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium, GIANT Genetic Investigation of Anthropometric Traits, GLGC Global Lipids Genetics Consortium, ICBP International Consortium for Blood Pressure, MAGIC Meta-Analyses of Glucose and Insulin-related traits Consortium, TAGC Tobacco and Genetics Consortium