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. 2018 May 16;19:65. doi: 10.1186/s12875-018-0754-1

Table 3.

Appropriateness of the treatment decision and use of diagnostic tests

First treatment decision (p-value = < 0.0001)a Final treatment decision (p-value = 0.04)b
Appropriate Overtreatment Undertreatment Appropriate Overtreatment Undertreatment
No culturec
(n = 54)
30(55) 21(39) 3(6) 30(55) 21(39) 3(6)
Culture performed in practice (n = 317) 176(56) 46(14) 95(30) 227(71) 76(24) 14(5)
Culture performed at hospital (n = 117) 71(61) 32(27) 14(12) 81(69) 24(21) 12(10)

Appropriate = prescribing antibiotics when reference test is positive and not prescribing antibiotics when reference test is negative

Ovrertreatment = prescribing antibiotics when reference test is negative

Undertreatment = not prescribing antibiotics when reference test is positive

Permutation LR test to assess whether treatment decision at the day of the index consultationa or at the day of the final treatment decisionb differs between groups: a) no culture, b) culture performed in practice, c) culture performed at hospital. Hierarchical model with practices as a random intercept and adjusted for: complicated versus uncomplicated UTI, offensive smell, anamnesis score, microscope and culture in practice availability

cWhen not performing culture, first treatment decision is the final treatment decision