Table 3.
Pearson correlation coefficients between AD biomarker and PC levels in the pramlintide challenge test
| Phospholipids | Aβ1-40 | Aβ1-42 | t-tau | |||
|---|---|---|---|---|---|---|
|
|
|
|
||||
| r | p values | r | p values | r | p values | |
| Associate with Aβ only | ||||||
| PC aa C38:5 | −0.19 | 0.02 | −0.31 | <0.01 | −0.07 | 0.37 |
| PC aa C40:5 | −0.19 | 0.02 | −0.19 | 0.02 | −0.02 | 0.92 |
| PC aa C40:2 | −0.20 | 0.01 | −0.28 | <0.01 | −0.02 | 0.77 |
| PC aa C42:4 | −0.19 | 0.02 | −0.29 | <0.01 | −0.11 | 0.18 |
| PC ae C36:5 | −0.32 | <0.01 | −0.21 | 0.01 | −0.03 | 0.72 |
| PC ae C38:6 | −0.24 | <0.01 | −0.13 | 0.11 | −0.06 | 0.49 |
| Associate with Aβ and t-tau | ||||||
| PC ae C38:0 | −0.34 | <0.01 | −0.32 | <0.01 | −0.31 | <0.01 |
| PC ae C38:1 | −0.25 | <0.01 | −0.26 | <0.01 | −0.26 | <0.01 |
| PC ae C40:5 | −0.17 | 0.03 | −0.25 | <0.01 | −0.23 | <0.01 |
| PC ae C38:3 | −0.24 | <0.01 | −0.29 | <0.01 | −0.21 | 0.01 |
| PC ae C38:2 | −0.24 | <0.01 | −0.12 | 0.13 | −0.22 | 0.01 |
| PC aa C32:0 | −0.20 | 0.02 | 0.06 | 0.45 | −0.19 | 0.02 |
| PC ae C40:3 | −0.21 | 0.01 | −0.39 | <0.01 | −0.17 | 0.04 |
| PC ae C40:1 | −0.30 | <0.01 | −0.28 | <0.01 | −0.17 | 0.04 |
Pearson univariate analyses were used to study the relationships between the typical AD biomarkers including Aβ1-40, Aβ1-42 and t-tau and PC biomarkers in plasma. R and p values are shown.