Fig. 3.

Multiple alignment of ORF5 amino acid sequences of representative isolates in each subgroup (Type 1 PRRSV) (a) and lineage (Type 2 PRRSV) (b). The representative isolates were selected based on main amino acid sequence of neutralizing epitope of Type 1 PRRSV (residues 29–35) [23] and Type 2 PRRSV (residues 37–45) [37]. The solid line box and gray color box represent neutralizing epitope and decoy epiotpe (residues 27–31) [57], respectively. The dot-line box indicates hypervariable regions [58]