Table 2.
ORF5 nucleotide (NT) and amino acid (AA) sequence similarity of subtype 1/subgroups of type 1 PRRSV (A) and lineages of type 2 PRRSV (B) to prototypes/vaccine strains
| Type | Isolated year | Subtype /Lineage | Sequence similarity | ||
| prototype | Vaccine strain | ||||
| Lelystad virus | DV (Porcilis® PRRS) | VP-046 (UNISTRAIN® PRRS) | |||
| (A) | |||||
| 1 | 2005-2009 | subtype 1-A | 87.8-90.9 (86.1-91.6)a | 87.6-91.1 (86.1-91.6) | 86.8-89.8 (85.6-91.1) |
| subtype 1-B | 85.8-86.9 (85.2-89.1) | 85.3-86.8 (84.2-88.1) | 85.5-87.5 (85.2-88.6) | ||
| 2013-2016 | subtype 1-A | 84.9-89.8 (82.2-91.6) | 85.0-89.6 (82.2-90.6) | 84.2-88.9 (81.7-92.6) | |
| subtype 1-B | 86.0 (85.6) | 85.5 (84.7) | 85.5 (86.1) | ||
| subtype 1-C | 93.9-98.4 (90.1-96.5) | 93-4-99.5 (89.6-98.5) | 93.7-99.8 (90.6-99.5) | ||
| Type | Isolated year | Subtype /Lineage | Sequence similarity | ||
| prototype | Vaccine strain | ||||
| VR2332 | Ingelvac PRRS MLV (Ingelvac® PRRS MLV) | P129 (Fostera® PRRS) | |||
| (B) | |||||
| 2 | 2003-2010 | lineage 4 | 88.9 (88.1) b | 88.9 (88.6) | 89.7 (89.1) |
| lineage 5 | 88.9-99.5 (88.1-99.0) | 89.9-99.8 (87.6-99.5) | 88.2-91.9 (88.1-92.5) | ||
| lineage kor A | 87.6-89.6 (82.6-88.6) | 86.7-89.7 (84.1-91.5) | 87.2-90.2 (86.1-93.0) | ||
| lineage kor C | 84.7-87.1 (84.1-88.6) | 84.7-87.1 (83.6-88.1) | 85.4-88.1 (84.1-89.1) | ||
| 2013-2016 | lineage 1 | 82.3-86.9 (81.7-87.6) | 84.9-86.1 (83.1-85.6) | 85.2-86.6 (84.6-86.6) | |
| lineage 5 | 87.6-99.3 (85.6-99.0) | 87.9-99.7 (87.1-99.5) | 86.7-91.7 (84.6-91.5) | ||
| lineage kor A | 85.1-89.1 (82.1-87.6) | 85.4-88.7 (82.6-88.1) | 85.6-89.2 (85.1-90.1) | ||
| lineage kor B | 85.7-89.1 (83.6-90.1) | 85.7-89.1 (83.1-89.6) | 86.1-89.1 (85.1-89.1) | ||
| lineage kor C | 85.2-86.4 (83.6-86.1) | 83.6-87.6 (81.2-87.1) | 82.6-86.9 (81.6-87.6) | ||
aNT and AA sequence similarity to Type 1 PRRSV prototypes (Lelystad) and vaccine strains (DV and VP-046). Parenthesis indicates AA sequence similarity
bNT and AA sequence similarity to Type 2 PRRSV prototypes (VR2332) and vaccine strains (Ingelvac PRRS MLV, P129). Parenthesis indicates AA sequence similarity