Figure 2.

Plectin-targeted peptide (PTP) liposomes bind to Plectin. (A) PTP peptide was conjugated to DSPE-PEG-maleimide via the thiol present on the C-terminus of the peptide. (B) Binding of PTP liposomes to the C-terminus of Plectin was measured using biolayer interferometry (BLI). The anti-His antibody coated sensors were used to bind his-tagged plectin fragment followed by association with no peptide, NCP and PTP liposomes. Association and dissociation response was seen by PTP liposomes but not with No peptide and NCP liposomes. (B, baseline).