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. Author manuscript; available in PMC: 2018 May 17.

Published in final edited form as: Circulation. 2018 Feb 22;137(19):e523–e557. doi: 10.1161/CIR.0000000000000564

Table 1.

Angiographic Prevalence of SCAD in ACS Cohorts

Reference	Year	Patients With SCAD, n	SCAD Prevalence as a Proportion of All ACS Cases, %	Women Among SCAD Cases, %	PA-SCAD, %	SCAD Prevalence in Subgroups With ACS	Methods, Population, Inclusion Criteria
Vanzetto et al³¹	2009	23	0.2 (0.6 women, 0.07 men)	74	0	8.7% SCAD among ACS in women ≤50 y	Systematic retrospective review of 11 605 angiograms Included type 1 SCAD only Atherosclerosis-related coronary dissection not excluded
Mortensen et al³⁰	2009	22	2.0	77	12	NR	Retrospective search for coded diagnoses in database of 32 969 angiograms; reviewed only those with prior SCAD diagnosis
Alfonso and Bastante¹⁴	2014	27	0.16	85	3.7	NR	Retrospective search for coded diagnoses among 16 813 first angiograms (2004–2010)
Saw et al¹⁵	2014	16	NR	100	NR	24.2% SCAD among ACS in women ≤50 y	Retrospective review of 177 angiograms in women ≤50 y representing 9% of angiograms (n=7605) performed during the study period (2009–2011)
Rashid et al¹⁶	2016	21	1.7	95.2	NR	22.5% SCAD among ACS in women ≤60 y	Retrospective search for coded diagnoses among 1332 angiograms (2012–2013)
Nakashima et al¹¹	2016	63	0.31	94	8.1	35% SCAD among ACS in women ≤50 y	Retrospective review of 20 195 angiograms (2000–2013) Excluded atherosclerosis-related coronary dissection Included type 2 SCAD Separate analysis for women ≤50 y with ACS (n=45)
Nishiguchi et al³²	2016	13	4	53.8	NR	NR	326 Selected ACS patients undergoing OCT (2008–2012) Atherosclerosis-related coronary dissection not excluded

ACS indicates acute coronary syndrome; NR, not reported; OCT, optical coherence tomography; PA-SCAD, pregnancy-associated spontaneous coronary artery dissection; and SCAD, spontaneous coronary artery dissection.