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. Author manuscript; available in PMC: 2018 May 17.
Published in final edited form as: Circulation. 2018 Feb 22;137(19):e523–e557. doi: 10.1161/CIR.0000000000000564

Table 4.

Screening Questions for SCAD-Associated Arteriopathies and Connective Tissue Disorders

Personal history (Have you ever been diagnosed with or experienced any of the following?)
 Early-onset hypertension
 Stroke or transient ischemic attack
 Pulsatile tinnitus
 Migraine headaches
 Renal infarction
 Subarachnoid hemorrhage
 Aneurysm (aortic, peripheral, brain)
 Dissection (aortic, peripheral)
 Rupture of hollow organs (intestinal, bladder, uterine)
 Pneumothorax
 Tendon or muscle rupture
 Joint dislocation
 Talipes equinovarus (clubfoot)
 Umbilical or inguinal hernia
 Scoliosis or pectus deformity
 Pregnancy complications (cervical incompetence, hemorrhage, uterine prolapse, hypertension)
 Poor wound healing
 Ectopia lentis
 Myopia
 Detached retina, early glaucoma, or early cataracts
 Tall stature
 Abnormality of cardiac valve (bicuspid aortic valve, mitral valve prolapse)
 Systemic inflammatory disease
Family history (Does anyone in your family have any of the following?)
 Dissection (coronary, aortic, peripheral)
 Inherited arteriopathy or connective tissue disorder (eg, vascular Ehlers-
 Danlos syndrome, Marfan syndrome, Loeys-Dietz syndrome)
Fibromuscular dysplasia
Aneurysm (aortic, peripheral, brain)
 Early stroke, early myocardial infarction, sudden cardiac death
Review of systems (Are you currently experiencing any of the following?)
 Headaches
 Pulsatile tinnitus
 Postprandial abdominal pain
 Flank pain
 Claudication
 Easy bruising
 Joint hypermobility or laxity

SCAD indicates spontaneous coronary artery dissection.