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. Author manuscript; available in PMC: 2018 Sep 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2017 Jun 14;331:130–134. doi: 10.1016/j.taap.2017.06.002

Figure 2.

Figure 2

Differential mRNA expression with arsenite exposure. A. Hierarchical clustering of mRNAs differentially expressed in HaCaT cells exposed to 0/100 nM arsenite for 7 weeks. Microarray hybridization data from 4 exposed and 4 unexposed cultures was analyzed using Parteck Genomic Suite to generate the heat map. Yellow indicates mRNAs induced by exposure, blue indicates suppression. B. Network of genes populating multiple dysregulated pathways at 7 weeks. Network of only direct interactions between genes populating multiple pathways at 7 weeks was built by Metacore™ software.