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. Author manuscript; available in PMC: 2019 Mar 6.
Published in final edited form as: Biochem J. 2018 Mar 6;475(5):873–886. doi: 10.1042/BCJ20170884

Figure 1. Overview of mutations in B-domain-deleted FVIII structure.

Figure 1

Individual FVIII domains are labeled. Mutated residues that give rise to potential ectopic N-glycosylation sequons are shown as spheres and labeled. Only oligosaccharides (GlcNAc2Man5) present in the crystallized molecule are shown in stick representation. Structural co-ordinates taken from PDB ID 2R7E.