Table 2. Demographic and other key characteristics of the RDCRN cohort (N = 290).
| Adults (n = 169) | Children (n = 121) | p-value2 | |
|---|---|---|---|
| Female gender—% (n)1 | 75.2 (124) | 47.0 (52) | <.0001 |
| Age, years: median (IQR) | 48 (35–57) | 12 (6–17) | <.0001 |
| Highest Education–% (n) | |||
| High school | 12.5 (21) | - | |
| Some college | 22.5 (38) | - | |
| College degree or equivalent | 42.7 (72) | - | |
| Graduate degree | 21.9 (37) | - | |
| No answer | 0.6 (1) | - | |
| Known mutation–% (n) | 0.4044 | ||
| Yes | 39.1 (66) | 43.0 (52) | |
| No | 21.3 (36) | 25.6 (31) | |
| Maybe | 38.5 (65) | 31.4 (38) | |
| No answer | 1.2 (2) | 0 (0) | |
| Mutation–% (n) | 0.0003 | ||
| mtDNA | 40.2 (68) | 33.1 (40) | |
| Nuclear DNA | 4.7 (8) | 20.7 (25) | |
| Don’t know | 49.1 (83) | 43.8 (53) | |
| No answer | 5.9 (10) | 2.5 (3) | |
| Family History–% (n) | 27.8 (47) | 25.6 (31) | 0.6782 |
| Previous Experience % (n) | |||
| Participated in research study | 30.2 (51) | 34.7 (42) | 0.3416 |
| Participated in clinical trial | 8.9 (15) | 13.2 (16) | 0.4618 |
| Acquaintance participated in clinical trial | 16.0 (27) | 33.9 (41) | 0.0018 |
1Cases with missing data are excluded for gender (4 adults and 10 children), and Previous Experience (maximum 4). No data are missing on other variables in the table.
2Comparison by two-sample t-test between Adult and Child groups is indicated by p-value.