Table 3. Associations (univariate analysis) of intraocular pressure with systemic parameters and ocular variables in the non-glaucomatous participants of the Beijing Eye Study 2011.
| Parameter | P-Value | B | 95% CI of B | Beta |
|---|---|---|---|---|
| Systematic Parameters: | ||||
| Age (Years) | <0.001 | -0.05* | -0.06, -0.04 | -0.18 |
| Gender (Men/Women) | 0.128 | -0.15 | -0.34, 0.04 | -0.03 |
| Rural / Urban Region of Habitation | <0.001 | -0.49* | -0.68, -0.30 | -0.09 |
| Level of Education | 0.53 | -0.03 | -0.12, 0.06 | -0.11 |
| Body Height (cm) | 0.055 | 0.01 | 0, 0.02 | 0.03 |
| Body Weight (kg) | <0.001 | 0.02* | 0.01, 0.03 | 0.09 |
| Body Mass Index (kg/m2) | <0.001 | 0.06* | 0.03, 0.08 | 0.08 |
| Waist Circumference (cm) | <0.001 | 0.02* | 0.01, 0.03 | 0.08 |
| Hip Circumference (cm) | <0.001 | 0.02* | 0.01, 0.04 | 0.06 |
| Blood Concentration Glucose (mmol/L) | <0.001 | 0.18* | 0.10, 0.25 | 0.10 |
| Glycosylated Hemoglobin HbA1c (%) | <0.001 | 0.22* | 0.10, 0.34 | 0.08 |
| Diabetes Mellitus | <0.001 | 0.47* | 0.21, 0.74 | 0.06 |
| Blood Concentration High-Density Lipoprotein (mmol/L) | 0.008 | -0.38 | -0.67, -0.10 | -0.06 |
| Blood Concentration Low-Density Lipoprotein (mmol/L) | <0.001 | 0.16* | 0.03, 0.28 | 0.05 |
| Blood Concentration Triglycerides (mmol/L) | <0.001 | 0.26* | 0.17, 0.35 | 0.11 |
| Blood Concentration Cholesterol (mmol/L) | <0.001 | 0.16* | 0.05, 0.28 | 0.06 |
| Systolic Blood Pressure (mm Hg) | <0.001 | 0.02* | 0.01, 0.02 | 0.12 |
| Diastolic Blood Pressure (mm Hg) | <0.001 | 0.04* | 0.03, 0.05 | 0.19 |
| Mean Blood Pressure (mm Hg) | <0.001 | 0.03* | 0.03, 0.04 | 0.17 |
| Arterial Hypertension | <0.001 | 0.31* | 0.12, 0.50 | 0.06 |
| Pulse Rate (Beats/min) | <0.001 | 0.03* | 0.02, 0.03 | 0.09 |
| Smoking Package Years | <0.001 | 0.01* | 0.01, 0.02 | 0.08 |
| Smoking (Ever) | <0.001 | 0.45* | 0.24, 0.65 | 0.08 |
| Alcohol Consumption Frequency | <0.001 | 0.11* | 0.15, 0.30 | 0.16 |
| Alcohol Consumption Quantity | <0.001 | 0.23* | 0.16, 0.31 | 0.11 |
| Aspirin Intake | 0.147 | -0.16 | -0.37, 0.06 | -0.03 |
| Ocular Parameters: | ||||
| Refractive Error (Diopters) | 0.022 | -0.05 | -0.10, -0.01 | -0.04 |
| Central Corneal Thickness (μm) | <0.001 | 0.04* | 0.03, 0.04 | 0.44 |
| Anterior Corneal Curvature (mm) | 0.19 | -0.26 | -0.64, 1.27 | -0.02 |
| Anterior Chamber Depth (mm) | 0.002 | -0.31 | -0.51, -0.11 | -0.06 |
| Lens Thickness (mm) | 0.001 | -0.48* | -0.77, -0.18 | -0.06 |
| Axial Length (mm) | 0.54 | 0.03 | -0.06, 0.12 | 0.11 |
| Optic Disc Area (mm2) | 0.838 | -0.04 | -0.38, 0.31 | -0.06 |
| Retinal Nerve Fiber Layer Thickness (μm) | 0.07 | -0.01 | -0.02, 0 | -0.03 |
| Early Age-Related Macular Degeneration | 0.086 | -0.30 | -0.65, -0.04 | -0.03 |
| Diabetic Retinopathy | 0.042 | 0.57 | 0.02, 1.12 | 0.04 |
| Retinal Vein Occlusion | 0.46 | -0.22 | -0.81, 0.37 | 0.01 |
95% CI: 95% Confidence Interval; B: Regression Coefficient; Beta: Standardized Correlation Coefficient
* Correlation is significant after Bonferroni correction for conducting multiple comparisons (P<0.0014)
Education was graded as 0: illiteracy; 1: half illiteracy; 2: primary school; 3: high school; 4: college or above college level.
Alcohol Consumption Frequency was graded as, 0: never drank alcohol; 1: former alcohol consumption but quitted; 2: alcohol consumption less than once per month; 3: alcohol consumption once per month; 4: alcohol consumption 2–3 times per month; 5: alcohol consumption once per week; 6: alcohol consumption 2–3 times per week; 7: alcohol consumption every day