Table 1.
Baseline Characteristics of Participants According to History of High Cholesterol and Statin use in Women in the Nurses’ Health Study (NHS) and in Men in the Health Professionals Follow-up Study (HPFS)
| History of High Cholesterol | Statin Use | |||
|---|---|---|---|---|
| No | Yes | No | Yes | |
| Women in NHS (2000) | ||||
| No. of participants | 22,862 | 34,376 | 45,119 | 12,119 |
| Age, years a | 64.1(7.1) | 66.1(6.9) | 64.9(7.1) | 67.0(6.8) |
| Family history of melanoma, % | 6.9 | 7.3 | 7.2 | 7.2 |
| Red/blonde hair, % | 14.8 | 14.4 | 14.6 | 14.5 |
| Painful burn/blisters reaction as a child/adolescent, % | 12.8 | 13.8 | 13.1 | 14.5 |
| No. of blistering sunburns | 8.2(6.9) | 8.5(6.8) | 8.4(6.9) | 8.6(6.9) |
| Use of sunscreen, % | 23.9 | 23.0 | 23.3 | 23.5 |
| Annual UV flux (×10−4 RB count) | 123.3(25.4) | 123.6(26.0) | 123.8(25.9) | 122.5(25.4) |
| Body mass index (kg/m2) | 26.2(5.4) | 27.4(5.4) | 26.6(5.4) | 28.2(5.4) |
| Physical activity level (metabolic-equivalents hrs/wk) | 18.3(23.0) | 16.2(21.2) | 17.5(21.8) | 15.5(22.8) |
| Current smoking, % | 10.8 | 9.2 | 9.8 | 9.8 |
| Menopausal status, % | 97.3 | 97.7 | 97.5 | 97.8 |
| Current postmenopausal hormones use, b % | 48.5 | 50.1 | 49.8 | 48.4 |
| Total energy intake (kcal/d) | 1741.6(534.0) | 1722.1(531.9) | 1738.3(533.9) | 1696.5(527.3) |
| Alcohol intake (g/d) | 5.4(9.3) | 4.7(9.0) | 5.1(9.2) | 4.3(8.5) |
| Total citrus intake (serving/d) | 0.8(0.6) | 0.8(0.6) | 0.8(0.6) | 0.8(0.6) |
| Statin use, % | 1.8 | 33.6 | - | - |
| History of high cholesterol, % | - | - | 50.6 | 96.9 |
| Men in HPFS (2000) | ||||
| No. of participants | 10,453 | 10,590 | 16,304 | 4,739 |
| Age, years a | 64.0(8.7) | 64.6(8.3) | 64.0(8.6) | 65.4(8.1) |
| Family history of melanoma, % | 4.5 | 4.9 | 4.7 | 4.9 |
| Red/blonde hair, % | 12.9 | 11.9 | 12.6 | 11.5 |
| Painful burn/blisters reaction as a child/adolescent, % | 21.7 | 21.8 | 22.1 | 20.8 |
| No. of blistering sunburns | 12.6(12.1) | 12.6(11.9) | 12.8(12.1) | 12.2(11.7) |
| Use of sunscreen, % | 58.5 | 60.3 | 58.9 | 60.8 |
| Annual UV flux (×10−4 RB count) | 129.4(27.3) | 129.5(27.5) | 129.5(27.4) | 129.1(27.5) |
| Body mass index (kg/m2) | 25.6(5.1) | 26.2(4.9) | 25.7(5.0) | 26.5(4.9) |
| Physical activity level (metabolic-equivalents hrs/wk) | 35.2(43.3) | 30.7(36.3) | 33.7(40.7) | 30.3(36.8) |
| Current smoking, % | 4.5 | 4.1 | 4.5 | 3.7 |
| Total energy intake (kcal/d) | 2019.7(545.1) | 1970.5(532.4) | 2013.4(543.3) | 1930.7(518.0) |
| Alcohol intake (g/d) | 10.4(13.8) | 11.0(13.9) | 10.7(14.0) | 10.8(13.2) |
| Total citrus intake (serving/d) | 1.0(0.7) | 0.9(0.7) | 0.9(0.7) | 0.9(0.7) |
| Statin use, % | 3.9 | 40.6 | - | - |
| History of high cholesterol, % | - | - | 38.4 | 91.7 |
Values are means (SD), or percentages and have been standardized to the age distribution of the study population.
a
Values are not age adjusted.
b
Percentages among postmenopausal women