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. Author manuscript; available in PMC: 2019 Apr 5.
Published in final edited form as: Cell. 2018 Apr 5;173(2):291–304.e6. doi: 10.1016/j.cell.2018.03.022

Key Resources Table

REAGENT or RESOURCE SOURCE IDENTIFIER
Antibodies
RPPA antibodies RPPA Core Facility, MD Anderson Cancer Center https://www.mdanderson.org/research/research-resources/core-facilities/functional-proteomics-rppa-core.html
Biological Samples
Tumor and normal tissue and blood samples TCGA Network https://portal.gdc.cancer.gov/legacy-archive/
Critical Commercial Assays
DNA/RNA AllPrep kit QIAGEN Cat# 80204
mirVana miRNA Isolation kit Ambion Cat# AM1560
QiaAmp blood midi kit QIAGEN Cat# 51185
AmpFISTR Identifiler kit Applied Biosystems Cat# A30737
RNA6000 nano Assay Agilent Cat# 5067-1511
Genome-Wide Human SNP Array 6.0 Affymetrix Cat# 901150
HumanMethylation450 Infinium Cat# WG-314-1002
HumanMethylation27 Infinium Cat# WG-311-2201
mRNA TruSeq kit Illumina Cat# RS-122-2001
Deposited Data
Raw genomic and clinical data NCI Genomic Data Commons https://portal.gdc.cancer.gov/legacy-archive/
MC3 mutation annotation file NCI Genomic Data Commons https://gdc.cancer.gov/about-data/publications/mc3-2017
Processed data files NCI Genomic Data Commons https://gdc.cancer.gov/about-data/publications/pancanatlas
Software and Algorithms
Copy number estimation Broad Institute http://archive.broadinstitute.org/cancer/cga/copynumber_pipeline
Significant focal copy number change – GISTIC 2.0 Mermel et al., 2011 http://software.broadinstitute.org/software/cprg/?q=node/31
Purity, ploidy, genome doubling - ABSOLUTE Carter et al., 2012 http://archive.broadinstitute.org/cancer/cga/absolute
Cluster analysis - ConsensusClusterPlus Wilkerson and Hayes, 2010 http://bioconductor.org/packages/release/bioc/html/ConsensusClusterPlus.html
Integrative clustering of multiple genomic data types (iCluster) Shen et al., 2009 https://www.mskcc.org/sites/www.mskcc.org/files/node/4281/documents/icluster-1.2.0.tar.gz
PARADIGM Vaske et al., 2010 http://sbenz.github.io/Paradigm/
TumorMap Newton et al., 2017 https://tumormap.ucsc.edu/
Mclust R package Scrucca et al., 2016 https://cran.r-project.org/web/packages/mclust/index.html
pheatmap v1.0.2 N/A https://www.rdocumentation.org/packages/pheatmap/versions/1.0.2
Mbatch (EB++) MD Anderson Cancer Center http://bioinformatics.mdanderson.org/main/TCGABatchEffects:Overview
DrL Alencar and Polley, 2011 http://wiki.cns.iu.edu/pages/viewpage.action?pageId=1704113
WGCNA Langfelder and Horvath, 2008 https://labs.genetics.ucla.edu/horvath/htdocs/CoexpressionNetwork/Rpackages/WGCNA/