Table 1.
Demographic and cognitive characteristics of participants self-identified as Black/AA or White
Total Mean (SD) or N,% |
Black/AA Mean (SD) or N,% |
White Mean (SD) or N,% |
t test χ2 |
p value | |
---|---|---|---|---|---|
N | 147 | 23 | 124 | — | — |
Sex | 87F, 59.2% | 19F, 82.6% | 68F, 54.8% | 5.097 | 0.024 |
Age (y) | 75.9 (6.9) | 73.1 (7.1) | 76.5 (6.8) | −2.076 | 0.047 |
PiB DVR | 1.21 (0.22) | 1.14 (0.14) | 1.22 (0.24) | −2.316 | 0.025 |
Aβ status | 46 Aβ+, 31.3% | 5 Aβ+, 21.7% | 41 Aβ+, 33.1% | 0.691 | 0.406 |
Education (y) | 15.9 (2.9) | 14.4 (2.7) | 16.1 (2.9) | −2.699 | 0.011 |
MMSE | 29.2 (0.97) | 29.0 (1.07) | 29.2 (0.96) | −1.165 | 0.254 |
CDR Sum of Boxes | 0.19 (0.35) | 0.20 (0.29) | 0.19 (0.36) | 0.031 | 0.976 |
(CDR = 0.5: N, %) | 12, 8.2% | 1, 4.3% | 11, 8.9% | −0.896 | 0.375 |
Composite Memory | 0.31 (0.93); 3 missing | 0.33 (0.89) | (0.31 (0.95); 3 missing | 0.130 | 0.897 |
Composite Executive | 0.16 (0.73); 3 missing | −0.33 (0.77) | 0.25 (0.69); 3 missing | −3.462 | 0.002 |
AA, African American; Aβ, amyloid-β; CDR, Clinical Dementia Rating; MMSE, Mini-Mental State Examination; PiB DVR, 11C-Pittsburg Compound B Distribution Volume Ratio; SD, standard deviation. NOTE: Chi-square (or Fisher) tests were used to test group differences on categorical variables; independent t tests were used to calculate group differences on continuous variables. All individuals received CDR 0 at study baseline. The proportion of CDR 0.5 reflects the number of individuals who received CDR 0.5 at the time of PET. Bold values indicate significant group differences (p < 0.05).