Table 2.
Race differences in regional FTP measurements
| Estimate | SE | t value | p value | Adj. p (14 tests) |
|
|---|---|---|---|---|---|
|
SUVR (pvc)
|
|||||
| CP | −0.606 | 0.168 | −3.619 | <10−3 | 0.006 |
| HC | −0.182 | 0.047 | −3.902 | <10−3 | 0.002 |
| HC residuals | −0.060 | 0.036 | −1.648 | 0.102 | >1.000 |
| AM | −0.001 | 0.050 | −0.011 | 0.991 | >1.000 |
| ER | −0.119 | 0.064 | −1.876 | 0.063 | 0.878 |
| FF | −0.077 | 0.039 | −1.986 | 0.049 | 0.686 |
| IT | −0.062 | 0.039 | −1.578 | 0.117 | >1.000 |
|
SUVR (non-pvc)
|
|||||
| CP | −0.194 | 0.056 | −3.442 | 0.001 | 0.011 |
| HC | −0.106 | 0.033 | −3.215 | 0.002 | 0.023 |
| HC residuals | −0.020 | 0.022 | −0.890 | 0.375 | >1.000 |
| AM | −0.026 | 0.027 | −0.945 | 0.346 | >1.000 |
| ER | −0.044 | 0.026 | −1.719 | 0.088 | >1.000 |
| FF | −0.025 | 0.019 | −1.330 | 0.186 | >1.000 |
| IT | −0.020 | 0.020 | −0.986 | 0.326 | >1.000 |
CP, choroid plexus; HC, hippocampus; HC residuals, hippocampus residualized for CP signal; AM, amygdala; ER, entorhinal; FF, fusiform; IT, inferior temporal; SE, standard error; Adj. p, p values adjusted for multiple comparison using the Bonferroni method; SUVR, standardized uptake value ratio; pvc, partial volume correction using geometric transfer matrix method. NOTE: Cerebellar cortex was used as reference for SUVR shown. Separate multiple linear regression models were run for each region, all models covarying for age, sex, PiB DVR, and education. Bold values indicate significant race differences in FTP measurements (p < 0.05).