Table 3. Metabolic and biochemical data of control and HSu groups for 9 weeks.
| Parameters | Control | HSu |
|---|---|---|
| Bodyweight (g) |
486.50±16.70 |
496.67±11.83 |
| Glycemic profile |
|
|
| Postprandial glycemia (mg/dl) |
200.00±7.87 |
245.00±8.38** |
| Fasting glycemia (mg/dl) |
96.81±1.72 |
101.64±1.24 |
| Glucose AUC-GTT (mg/dl/120 min) |
29,209.17±2429.31 |
43,438.60±3905.57* |
| HbA1c (%) |
3.78±0.037 |
3.9±0.045 |
| Insulinemic profile and insulin resistance |
|
|
| Fasting insulin (µg/l) |
2.03±0.18 |
2.59±0.61 |
| HOMA-IR (x10−5) |
1.40±0.14 |
2.47±0.35* |
| Glucose ITT 0 min (mg/dl) |
108.20±4.74 |
118.00±2.47 |
| Glucose ITT 15 min (mg/dl) |
97.50±6.61 |
122.20±6.91* |
| Glucose ITT 30 min (mg/dl) |
78.17±2.0 |
91.50±4.06* |
| Glucose ITT 45 min (mg/dl) |
75.17±3.79 |
87.83±3.18* |
| Glucose ITT 60 min (mg/dl) |
67.00±4.83 |
75.67±6.92 |
| Glucose ITT 120 min (mg/dl) |
65.33±6.90 |
90.5±11.55 |
| Lipid profile |
|
|
| Total-Cholesterol (mg/dl) |
61.50±3.15 |
60.83±4.80 |
| Triglycerides (mg/dl) | 146.70±17.84 | 235.3±38.87* |
Data are expressed as mean ± SEM, *p<0.05; **p<0.01 versus the Control group (n=5/6). AUC, area under the curve; GTT, glucose tolerance test; HbA1c, glycated hemoglobina; HOMA-IR, Homeostatic Model Assessment for Insulin Resistance; ITT, insulin tolerance test.