Table 2.

Changes in reported quarterly rates of mediastinitis following coronary artery bypass graft and deep space surgical site infection after knee replacement over time.

Estimated change in reported infection rate	Odds Ratio (95% CI)	P value
Targeted healthcare-associated infection: mediastinitis following CABG
Slope in pre-program period	0.98 (0.94 – 1.03)	0.49
Slope in post-program period	0.99 (0.97 – 1.02)	0.63
Change at time of program implementation	1.06 (0.64 – 1.75)	0.83
Change in slope (post- vs. pre-program period)	1.01 (0.96 – 1.07)	0.70
Non-targeted healthcare-associated infection: deep space SSI after knee replacement
Slope in pre-program period	1.00 (0.96 – 1.05)	0.95
Slope in post-program period	1.00 (0.99 – 1.02)	0.67
Change at time of program implementation	0.91 (0.62 – 1.36)	0.66
Change in slope (post- vs. pre-program period)	1.00 (0.95 – 1.05)	0.96

Note: Deep space SSI after knee replacement includes infections of the joint or bursa, osteomyelitis, or periprosthetic joint infection.