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. 2018 May 17;8:7792. doi: 10.1038/s41598-018-26096-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Pre-operative MRSI data acquired from a 72-year-old female with a biopsy confirmed IDH-2 mutant oligodendroglioma affecting the left temporal lobe. To assess 2-HG concentration, the TE was changed from 32 to 110 ms. All other acquisition parameters were consistent with those reported above. 2-HG:tCr, tCho:tCr, and NAA:tCr ratio maps show marked local disturbance in normal ratios in the affected area. In metabolite images, non-brain tissue was masked based on the water image.