Table 3.

Prediction of BIT pIC50 from EI pIC50.

Compound Number	EI pIC50	Actual BIT pIC50	Predicted BIT pIC50
43	7.1	7.1	6.8
37	6.1	6.3	6
41	6.5	6.5	6.4
42	7.1	7	6.8

EI and BIT pIC50’s were determined from EIA and SMFA respectively for same set of compounds used in Table 2. Using EI pIC50 values in Eq. 7 the BITpIC50 was predicted and compared with the actual values obtained.