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. 2018 May 17;8:7753. doi: 10.1038/s41598-018-25964-x

Figure 4.

Figure 4

Failure to reach blastocyst in POU5F1 knockout embryos is associated with altered CDX2 expression. (A) Characterization of CDX2 (red) expression in D3, 5 and 7.5 morulas from injected control groups. (B) CDX2 (red) staining patterns detected in D7.5 arrested POU5F1-edited and unedited embryos from the targeted knockout and injected control groups. Scale bar = 100 µm.