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. 2018 May 17;8:7793. doi: 10.1038/s41598-018-26173-2

Table 2.

List of the mean values of the considered cardiovascular parameters in the subsequent phases of the pilot study.

Parameter Phase
1 2 3 4 5 6 7
HR (bpm) 72.65 84.90** 67.69 84.81§ 67.65§ 100.49** 64.12
SD ±12.01 ±16.52 ±8.05 ±11.99 ±11.02 ±14.75 ±10.00
Rel HR (%) 0 16.87** −5.98 17.68§ −6.70§ 39.49** −11.19
SD 0 ±11.04 ±7.18 ±10.78 ±4.51 ±14.65 ±8.65
IBI (ms) 856.07 742.87** 906.83 725.21§ 917.71§ 614.53** 967.23
SD ±149.01 ±138.30 ±117.25 ±97.43 ±151.74 ±88.87 ±156.26
Rel IBI (%) 0 −13.15** 6.81 −14.53§ 7.42§ −27.58** 13.66
SD 0 ±7.80 ±7.59 ±8.26 ±5.43 ±7.70 ±11.44
SBP (mmHg) 123.39 117.62 126.08 130.47 126.42 132.54* 131.63*
SD ±16.01 ±14.52 ±18.83 ±20.68 ±17.41 ±25.57 ±25.47
Rel SBP (%) 0 −4.30 2.85 5.96 2.76 7.31* 6.37*
SD 0 ±7.79 ±14.69 ±11.18 ±10.42 ±12.01 ±10.58
DBP (mmHg) 76.31 73.31 71.40 90.02 72.54 94.06 71.83
SD ±17.32 ±11.11 ±10.95 ±11.71 ±17.94 ±11.83 ±12.18
Rel DBP (%) 0 −1.11 −1.66 22.56 −1.986 28.78 −1.99
SD 0 ±17.76 ±30.22 ±28.18 ±28.76 ±33.02 ±27.11
MAP (mmHg) 93.02 87.00 90.68 103.47 91.68 105.12* 91.93
SD ±17.14 ±13.48 ±13.41 ±14.60 ±15.44 ±13.97 ±15.17
Rel MAP (%) 0 −5.39 −0.70 12.73 −0.35 15.04* 0.21
SD 0 ±11.64 ±17.47 ±14.19 ±15.29 ±18.52 ±16.27
SV (ml) 88.98 69.36* 102.04 54.79 105.38 42.65§ 107.49*
SD ±32.77 ±26.04 ±24.60 ±22.90 ±65.52 ±15.61 ±38.31
Rel SV (%) 0 −19.75* 26.37 −34.09 20.23 −47.50§ 28.51*
SD 0 ±26.43 ±45.90 ±30.00 ±56.43 ±25.05 ±46.22
CO (l/min) 6.50 5.85* 7.03 4.58* 6.90 4.31 7.03
SD ±2.34 ±1.93 ±2.42 ±1.70 ±3.95 ±1.55 ±2.66
Rel CO (%) 0 −7.16* 15.36 −25.49* 8.44 −29.52 12.15
SD 0 ±26.36 ±40.13 ±30.00 ±52.04 ±28.27 ±36.89
LVET (ms) 325.25 255.28** 328.76 256.89** 331.55 241.8§ 333.84
SD ±15.84 ±26.47 ±14.21 ±22.77 ±17.66 ±34.65 ±17.97
Rel LVET (%) 0 −21.45** 1.18 −20.87** 2.01 −25.35§ 2.79
SD 0 ±7.85 ±3.96 ±7.70 ±4.51 ±12.79 ±5.99
RPP (mmHg/min) 0.92 × 104 1.03 × 104† 0.86 × 104 1.11 × 10 0.86 × 104† 1.36 × 104** 0.87 × 104
SD ±0.23 × 104 ±0.22 × 104 ±0.19 × 104 ±0.20 × 104 ±0.21 × 104 ±0.31 × 104 ±0.22 × 104
Rel RPP (%) 0 12.28 × 104† −5.23 × 104 23.07 × 10 −6.70 × 104† 51.05 × 104** −3.43 × 104
SD 0 ±12.44 × 104 ±14.66 × 104 ±19.73 × 104 ±10.59 × 104 ±36.55 × 104 ±24.02 × 104
TPR (MU) 1.20 1.03 0.91 1.62* 1.11 1.68 0.90*
SD ±0.61 ±0.48 ±0.33 ±0.73 ±0.46 ±0.61 ±0.35
Rel TPR (%) 0 −0.31 2.25 67.55* 6.14 74.28 −8.46*
SD 0 ±49.98 ±84.36 ±103.12 ±53.95 ±101.34 ±56.28

The significance levels for changes in the mean values obtained in the subsequent phases are shown in relation to those obtained in phase 1.

Rel - relative values calculated with reference to the initial level in phase 1.

MU - medical units.

Levels of significance.

*p ≤ 0.05; p ≤ 0.01; p ≤ 0.005; §p ≤ 0.0005; **p ≤ 0.00005.