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Vigilance states modulation of neuronal activity in the VTA, SNM and SNL.
| Midbrain Structure | Wakefulness | REM Sleep |
|---|---|---|
| SN-Lateral (n = 6) | 137.4 ± 4.1* | 141 ± 4.6* |
| SN-Medial (n = 5) | 145.2 ± 6* | 149.1 ± 9.1* |
| VTA (n = 6) | 183.7 ± 28.7* | 145.5 ± 6.2* |
MUA activity is calculated as a percentage of the mean activity during NREM sleep over 24 h (set as 100). All midbrain structures increased their neuronal firing rate during wakefulness and REM sleep. *p < 0.001.
