Table 3.
Test characteristics of the four antigen assays
| Platelia | Platelia plus | Serion | Fungitell | |||||
|---|---|---|---|---|---|---|---|---|
| Proven IC | Proven, probable or possible IC | Proven IC | Proven, probable or possible IC | Proven IC | Proven, probable or possible IC | Proven IC | Proven, probable or possible IC | |
| True positives | 13 | 29 | 11 | 20 | 12 | 26 | 12 | 34 |
| True negatives | 709 | 709 | 259 | 259 | 710 | 710 | 170 | 170 |
| False negatives (false-negative rate) | 7 (35%) | 41 (58.5%) | 2 (15.4%) | 31 (60.8%) | 11 (47.8%) | 44 (62.9%) | 0 (0%) | 17 (33.3%) |
| False positives (false-positive rate) | 14 (1.9%) | 14 (1.9%) | 31 (10.7%) | 31 (10.7%) | 17 (2.3%) | 17 (2.3%) | 123 (42%) | 123 (42%) |
| Total | 743 | 793 | 303 | 341 | 750 | 797 | 305 | 344 |
| Sensitivity | 0.65 | 0.41 | 0.85 | 0.39 | 0.52 | 0.37 | 1 | 0.67 |
| Specificity | 0.98 | 0.98 | 0.89 | 0.89 | 0.98 | 0.98 | 0.58 | 0.58 |
| PPV | 0.48 | 0.67 | 0.26 | 0.39 | 0.41 | 0.60 | 0.09 | 0.22 |
| NPV | 0.99 | 0.95 | 0.99 | 0.89 | 0.98 | 0.94 | 1 | 0.91 |