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. 2018 Apr 6;32(2):169–173. doi: 10.1007/s10557-018-6787-9

Table 1.

Results summary. SRCL sinus rhythm cycle length, hRA-CSos intraatrial conduction time, hRA-CSd interatrial conducion time, RA-ERP right atrium refractory period, LA-ERP left atrium refractory, AVN-ERP atrioventricular node refractory period, WP Wenckebach point, SNRT sinus node recovery period, BPsys systolic blood pressure, BPdias diastolic blood pressure

Baseline 100 mg P 200 mg P 300 mg P
SRCL (ms) 772.8 ± 38.47 703.4 ± 32.51 < 0.01 703.5 ± 31.03 < 0.05 702.9 ± 31.31 < 0.01
AH (ms) 90.26 ± 5.28 93.93 ± 6.47 ns 96.06 ± 6.34 ns 97.13 ± 5.59 ns
HV (ms) 49.3 ± 2.22 54 ± 3.09 ns 56.46 ± 2.89 < 0.001 58.53 ± 2.89 < 0.001
QRS (ms) 91.93 ± 4.84 95.13 ± 5.64 ns 99.27 ± 6.43 < 0.01 102.73 ± 6.21 < 0.001
QT (ms) 356 ± 7.54 363.33 ± 7.87 ns 363.33 ± 7.29 ns 369.13 ± 7.20 < 0.001
QTc (ms) 408.07 ± 38.18 434.67 ± 9.89 < 0.05 435.73 ± 20.51 < 0.01 443 ± 3.53 < 0.001
hRA-Csos (ms) 83.2 ± 5.39 87.87 ± 5.68 ns 91.4 ± 5.1 < 0.01 93.13 ± 5.67 < 0.001
hRA-CSd (ms) 117.13 ± 6.75 122.8 ± 7.13 ns 126.67 ± 6.64 < 0.001 129.73 ± 7.15 < 0.001
AVN-ERP (ms) 290.67 ± 20.15 298.67 ± 18.97 ns 278 ± 18.24 ns 252 ± 22.39 ns
RA-ERP (ms) 210.67 ± 7.27 232 ± 6.77 ns 239.33 ± 8.31 < 0.05 246.67 ± 8.71 < 0.001
LA-ERP (ms) 230.67 ± 4.52 236.67 ± 4.65 ns 243.33 ± 4.75 < 0.05 246 ± 5.84 < 0.01
WP (bpm) 169.53 ± 6.99 168.73 ± 7.49 ns 168.2 ± 7.71 ns 168.2 ± 7.63 ns
SNRT (ms) 924.2 ± 47.55 N/A N/A 899.53 ± 40.60 ns
BPsys (mmHg) 123.46 ± 15.55 N/A N/A 120.47 ± 13.43 ns
BPdias (mmHg) 71.33 ± 17.67 N/A N/A 73 ± 15.55 ns

N/A not available, ns not significant