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. 2018 May 11;9:1013. doi: 10.3389/fimmu.2018.01013

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Copyright © 2018 Wang, Lu, Zhang, Wu, Yan, Dong and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The expression of tumor necrosis factor-alpha (TNF-α) in serum; (B) the expression of IL-6 in serum. *p < 0.05 vs. control; ^#p < 0.05 vs. collagen-induced arthritis (CIA). The results indicated that the production of pro-inflammatory cytokines TNF-α and IL-6 in mice which received high-density lipoprotein (HDL) decreased 45.14 and 35.02%, respectively.