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Egr3 is not required for development of normal numbers of hippocampal neurons. Sample montaged photomicrographs from the hippocampus of anti-NeuN stained (A) WT and (B) Egr3–/– mice show no obvious signs of changes in gross morphology (scale bar = 100 μm). Consistent with this observation, (C) quantification of NeuN+ cells (n = 6 animals/genotype) demonstrated no significant differences in neuron density in any hippocampal region between WT (black) and Egr3–/– (gray) mice.
