Table 1.
RBC eNOS KO | RBC Nrf2 KO | RBC WT | |
---|---|---|---|
GSH (nM) | 3.76*106 ± 0.26*106 | 3.77*106 ± 0.14*106 | 3.93*106 ± 0.23*106 |
GSSG (nM) | 946.0 ± 161.3 | 781.5 ± 68.6 | 1057.7 ± 46.4 |
Total GSH (nM) | 3.76*106 ± 0.26*106 | 3.77*106 ± 0.14*106 | 3.94*106 ± 0.23*106 |
GSH/GSSG | 3974.6 | 4821.5 | 3718.3 |
Intracellular reduced/”free” GSH, oxidized GSH (GSH disulfide), total GSH (calculated by GSH and GSH disulfide levels), and ratio of GSH to GSH disulfide measured in RBCs by mass spectroscopy.