Figure 5. Relations of discrete probability distributions on log-normal FLNe distribution variabilities and connectivity profiles.

In A, B, C, the hypothetical results of 1000 injections were simulated according to a Poisson, Negative Binomial (dispersion parameter θ = 7) and Geometric distributions (θ = 1). (D) The standard deviation is plotted as a function of the means calculated for the simulated injections from A, B and C with the colors indicating the distribution from which the calculations were made. (E, F) Example of the effect of overdispersion on the reliability of projections in present data (E) and in Oh et al. 2014 (F). In both plots a single injection in V1 (VISp, respectively) was taken and the areas were ordered according to their strengths. The difference between the log of the maximum and of the nonzero minimum was then divided into four intervals (delimited by dashed horizontal lines), and assigned the log of the FLNe to the corresponding intervals, forming four groups. Next, the strengths of the corresponding areas from the other repeats were used to obtain the boxplots. The stars represent the significance levels attained of the p values of one-sided permutation tests for each pair of consecutive groups, with the null hypothesis that the mean of the group on the left is larger than the mean of the group on the right. Notice that the present data are all restricted to the initial intervals (within the limits of the dashed horizontal lines), while the data from Oh et al. 2014 in all but one case cross these limits.