Fig. 4.
Comparison of Energy Expenditure Effects of OX-SR and OX-SR-Glu3. Total oxygen consumption over 12 h (A), food intake over 24 h (B), body weight change over 24 h (C) and average RER over 12 h (D) following an injection in male Wistar rats injected of vehicle, OX-SR (40 nmol/kg) or OX-SR-Glu3 (40 nmol/kg) in CLAMS metabolic cages. Animals had free access to standard laboratory chow throughout. Data expressed as mean ± SEM. n = 9–11. Statistical analysis was performed using one-way ANOVA with post-hoc Tukey’s multiple comparison test.* p < 0.05 ** p < 0.01, *** p < 0.001.