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. 2018 May 11;9:468. doi: 10.3389/fphar.2018.00468

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Copyright © 2018 Rodríguez-Nogales, Algieri, Garrido-Mesa, Vezza, Utrilla, Chueca, Fernández-Caballero, García, Rodríguez-Cabezas and Gálvez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biochemical evaluation of the effects of Escherichia coli Nissle 1917 (EcN); the expression of (A) miR-150, (B) miR-155, (C) miR-223, (D) miR-143, and (E) miR-375 was quantified by real-time PCR. Fold changes are expressed as means ± SEM. Non-colitic group (n = 10), DSS-colitic group (n = 10), and EcN group (n = 10). Statistical analysis was performed with one-way ANOVA followed by Tukey’s test. Bars with different letters are significantly different (p < 0.05). Non-colitic: untreated healthy group (n = 10); DSS-colitic: untreated DSS-induced colitic group (n = 10) and EcN: DSS-induced colitic group treated with probiotic (n = 10).