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. 2018 May 11;9:709. doi: 10.3389/fpsyg.2018.00709

Table 3B.

Summary of studies using healthy and elite populations (additive studies).

Article Sample (completed) Device Active Control Near transfer test Far transfer* test Retention test Independent of company Cognitive outcomes Findings
Brehmer et al., 2012 55 younger adults (mean 26.0 yrs) and 45 older adults (mean 63.8 yrs) Cogmed Non-adaptive version of training task Yes No Yes No WM, sustained attention, inhibition, STM, reasoning TG showed greater improvement in WM tasks (forwards and backwards span) than controls (p = 0.01 and p < 0.001). TG also showed greater improvement in sustained attention, but not inhibition, STM or reasoning. Group differences remained at 3 month follow-up
Dunning and Holmes, 2014 45 students (18–21 yrs) Cogmed Non-adaptive version of training task Yes No No Yes WM, STM Interaction effects indicated greater gains on verbal and visuospatial WM (span tasks) and verbal STM for the TG over active and passive controls (ps < 0.05), but not for visuospatial STM.
Gibson et al., 2013 20 undergraduate students Cogmed No Yes No No Yes WM Two TGs displayed significantly greater recall on items from primary (p < 0.05) and secondary memory (p < 0.01) than passive controls.
Hardy et al., 2011 23 participants (mean 57.0 yrs) Lumosity No Yes No No No Spatial WM and divided visual attention TG improved significantly from pre to post in divided attention (p < 0.001) and significantly more than controls (p = 0.027). TG improved significantly in forward spatial WM, (p = 0.032), significantly more than controls. They also improved reverse spatial span (p = 0.008). There was no change in letter memory, (p = 0.517).
Hardy et al., 2015 4715 Lumosity users (18–80 years; 39.2 ± 15.1 yrs) Lumosity Crossword Puzzles Yes Yes (SR) No No Overall battery (inc. STM, WM, grammatical and arithmetic reasoning, response inhibition, selective attention) Significantly greater improvement on battery in TG (p < 0.001). Largest effects in inhibition and arithmetic reasoning. Also significantly greater improvement in self-reported cognition and emotional status, (p < 0.001).
McNab et al., 2009 13 healthy males (20–28 yrs) Cogmed No Yes No No No WM Training improved WM capacity (p < 0.001). No comparison group. Improvements were associated with cortical dopamine binding.
Metzler-Baddeley et al., 2016 40 adults (26.5 ± 6.6 yrs) Cogmed Non-adaptive version of training task Yes Yes No Yes WM, inhibition, grammatical reasoning, general intelligence, multi-tasking The TG showed significantly greater improvement in two measures of WM (ps < 0.001), but not in tests of inhibition, grammatical reasoning, general intelligence, and multi-tasking. Adaptive training related to structural brain changes measured through Magnetic Resonance Imaging.
Nouchi et al., 2013 32 young adults (20.7 ± 1.2 yrs) Nintendo Brain Age Video game Yes No No Yes Fluid intelligence, EF, WM, STM, processing speed The TG showed greater improvements than active controls in EF (ps < 0.001–0.002), WM (OSPAN) (ps = 0.003–0.008) and processing speed (symbol search) (ps = 0.004–0.006). Active controls showed greater improvement in sustained attention (p = 0.01) and visuo-spatial ability (p = 0.009). No improvement in fluid intelligence or STM for either group.
Parsons et al., 2016 20 University students (23.3 ± 2.7 yrs) Neurotracker No Yes Yes No No Selective and sustained attention, processing speed, STM, WM, inhibition TG showed significant improvements in sustained attention (p = 0.007), inhibition (p = 0.004), WM (p = 0.02), and STM (p = 0.008) (WAIS tests). TG also showed decreased EEG power in theta, alpha and delta bands, primarily in frontal cortex.
Romeas et al., 2016 23 soccer players (21.7 ± 0.5 yrs) Neurotracker Soccer videos No Yes No No None TG showed significantly greater improvement than controls in passing accuracy (p = 0.044), but not dribbling or shooting. There was a significant increase in self-reported confidence in decision making in the TG (p = 0.012) but not controls.
Vartanian et al., 2016 41 Armed Forces personnel (21–50 years) Neurotracker Dual n-back Yes No No Yes WM TG showed significant increases in word (p = 0.005), visual (p = 0.05), and matrix (p = 0.015) span tasks. There was no improvement in active and passive control groups.
*

Transfer to tasks other than laboratory cognitive tests.

SR, self-report outcome; WM, working memory; STM, short-term memory; EF, executive function; TG, treatment group; OSPAN, Operation Span task; WCST, Wisconsin card Sorting Task; WAIS, Wechsler Adult Intelligence Scale; ADHD, Attention deficit hyperactivity disorder, MS, Multiple Sclerosis; ps, multiple p-values.

Quality assessment color key: Strong (80+%)Fairly strong (7079%)Moderate  (6069%)Weak  (5059-%)Very weak (46049%)