Table 4.
Food and drug administration (FDA) classification of severity of adverse drug reactions
| Type of ADR | (%) |
Severity of ADRs
|
|||
|---|---|---|---|---|---|
| Mild | Moderate | Severe | Very severe | ||
| Chest pain | 62.1% | 16.2 | 21.7 | ||
| Hypotension | 65.4% | 15.7 | 18.5 | 0.5 | |
| Coughing | 87.1% | 4.6 | 8.3 | ||
| Ecchymose | 89.9% | 3.2 | 8.3 | ||
| Pain in the extremities | 89.9% | 3.7 | 6.4 | ||
| Nausea and vomiting | 89.9% | 4.6 | 5.5 | ||
| Bronchospasm | 90.1% | 1.9 | 4.2 | 3.8 | |
| Bradycardia | 90.3% | 4.6 | 4.6 | 0.5 | |
| Sweating | 90.3% | 9.7 | |||
| Tachycardia | 91.2% | 4.2 | 4.6 | ||
| Fever and chill | 91.6% | 1.9 | 6.5 | ||
| Ventricular fibrillation | 92.6% | 2.3 | 5.1 | ||
| Headache | 94% | 2.3 | 3.7 | ||
| Hypertension | 94.9% | 2.8 | 2.3 | ||
| Bleeding | 94.9% | 2.3 | 0.9 | 1.9 | |
| Agitation | 95.4% | 4.6 | |||
| Back pain | 95.7% | 1.5 | 2.8 | ||
| Abdominal cramp | 95.8% | 1.4 | 2.8 | ||
| Gastrointestinal bleeding | 95.8% | 2.8 | 1.4 | ||
| Pulmonary edema | 96.3% | 3.2 | 0.5 | ||
| Epigastric pain | 96.3% | 2.3 | 1.4 | ||
| Constipation | 96.3% | 0.9 | 2.8 | ||
| Hematuria | 96.7% | 0.5 | 0.9 | 1.9 | |
| Hemoptysis | 96.7% | 0.5 | 2.8 | ||
| Allergy and erythema | 97.2% | 0.9 | 1.9 | ||
| Phlebitis | 97.2% | 0.5 | 2.3 | ||
| Cardiogenic shock | 97.2% | 0.5 | 2.3 | ||
| Atrial fibrillation | 97.6% | 0.5 | 1.9 | ||
| Swelling and edema in the extremities | 98.1% | 1.9 | |||
| Dry mucosa | 98.6% | 1.4 | |||
| Itching | 98.6% | 1.4 | |||
| Stroke | 98.6% | 1.4 | |||
| Hypoxic encephalopathy | 99% | 0.5 | 0.5 | ||
| Diarrhea | 99.1% | 0.4 | 0.5 | ||